Osteogenesis Imperfecta

Osteogenesis imperfecta Osteogenesis imperfecta (OI) is a r atomic number 18 inherited disorder of collagen synthesis associated with all-inclusive spectrum of musculoskeletal problems, most notably bowing and fractures of the extremities, muscle weakness, lassitude in the ligaments, and spinal deformities.(Binder, 386). otherwise collagen-containing skeletal tissues, such as the sclerae, the teeth, and the heart valves argon as well as affected to a variable measure degree. OI has a common feature of bony fragility associated with severe formation of collagen by osteoblasts and fibroblasts(Smith, 1983, 13).

This disease, involving defective de velopment of the connective tissues, is unremarkably the result of the autosomal dominant gene, but can excessively be the result of the autosomal recessive gene. Spontaneous mutations are common and the clinical presentation of the disease remains to be quite broad (Binder, 386). OI is most commonly referred to as breakable bones,” but other names include: fragilitas o...If you want to buzz off a full essay, order it on our website: OrderEssay.net

If you want to get a full information about our service, visit our page: write my essay